NEW Treatment For Meth Addiction Proves Effective - naltrexone and bupropion #meth #methaddiction
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For the first time, a medication regime has been found effective for some patients with meth addiction in a large, placebo-controlled trial.
In the trial, patients in clinics around the U.S. suffering from methamphetamine use disorder were treated for 12 weeks with a combination of medications — naltrexone and bupropion — or placebo. The treatment helped 13.4% of patients with their addiction, compared with 2.5% of the placebo group.
The treatment regimen in the trial combined two medications that have been studied separately for treating methamphetamine addiction with limited success.
Patients received injections of extended-release naltrexone and oral doses of bupropion. Naltrexone, which is already used for treating opioid addiction, blocks opioid receptors in the brain and is proven to reduce cravings in some patients. Bupropion is often used to treat depression.
This clinical trial was successful enough that the National Institute on Drug Addiction's Volkow says she expects to move forward toward securing FDA approval. Meanwhile, she predicts some clinicians helping people in recovery will begin using the treatment immediately.